Abstract

ALVAREZ AMADOR, Héctor Eduardo et al. Ceftriaxone´s use in monodoses for the treatment of otitis media acute suppurativa in pediatric age patients. AMC [online]. 2011, vol.15, n.1, pp.1-11. ISSN 1025-0255.

Background: otitis media acute suppurativa is very frequent disease in pediatrics.  The 80% of children in preschool age and 50% of infants make ear suppuration twice a year. Objective: to evaluate the efficacy of an only dose of ceftriaxone in pediatric patients with otitis media acute suppurativa. Method: a phase IV clinical trial was performed, during the second semester of 2008 to 51 children admitted with otitis media acute suppurativa as diagnosis, at the provincial pediatric hospital of Camagüey Eduardo Agramonte Piña. Results: a slight increase of the masculine sex was found; with significant prevalence of the white race (44,86%). There was a high incidence in patients under one year (29) for 56,9%. The 58,8% (30) of patients previously received antimicrobial treatment. The most frequent antimicrobial treatment used was amoxicillin (44,1%), penicillin (20,5%) and claforan (11,7%). More than the 66% presented a favorable evolution within 72 hours next to the treatment with ceftriaxone monodoses. In 48 of studied patients a favorable otoscopic evolution was obtained, what corresponded to 94,12% of studied cases. Conclusions: a favorable evolution was achieved within 72 hours following to the treatment with ceftriaxone monodoses in more than the half of cases.

Keywords : CEFTRIAXONE [terapeutic use]; OTITIS MEDIA; ANTIMICROBIAL, CATIONIC PEPTIDES; CHILD; CLINICAL TRIAL, PHASE IV.

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