Abstract

QUINONES HERNANDEZ, Judith; CHAVEZ VIAMONTES, José Ángel  and  BERNARDEZ HERNANDEZ, Oscar. Stevens-Johnson syndrome: a case presentation. AMC [online]. 2011, vol.15, n.3, pp.576-584. ISSN 1025-0255.

Introduction: Stevens-Johnson syndrome is an acute inflammatory disease, characterized by an erythema multiforme bullosum of the skin and other organs; it is considered the initial stage of a dermic reaction whose severest presentation is toxic epidermal necrolysis. Its cause is linked to the use of some drugs in a 60 %, as well as infectious causes and some genetic predisposing factors. Clinical case: a 69 years old woman with diagnosis of tonsillitis who received treatment with ciprofloxacin, to the twenty four hours of evolution the patient evolved a severe Stevens-Johnson syndrome with skin, ocular and oral mucosa manifestations that evolved to a toxic epidermal necrolysis, accompanied by other complications and had a fatal outcome. Discussion: Stevens-Johnson syndrome and toxic epidermal necrolysis may appeared with a morbilliform eruption that may develop to a necrosis of the skin, affecting digestive tube, trachea, the bronchi, urinary tract, vagina and conjunctivas. In the critical cases may appear complications like persistent ocular injuries, pneumonia, esophageal stenosis, chronic renal insufficiency, hepatic insufficiency, hematological disorders, massive losses of fluids by trans-epidermal via and sepsis, the last one constitute the main cause of death.

Keywords : STEVENS-JOHNSON SYNDRME [diagnosis]; EPIDERMAL NECROLYSIS, TOXIC; CIPROFLOXACIN; CASE REPORTS.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )