Abstract

ALVAREZ LOPEZ, Alejandro  and  GARCIA LORENZO, Yenima. Antimicrobial prophylaxis in orthopedics: report of 93 patients. AMC [online]. 2012, vol.16, n.1, pp.35-44. ISSN 1025-0255.

Background: postoperative infection is a complication with a high social and economic cost which may reach sometimes the death of the patient, therefore the importance of preventing and treating this disease in time. Objective: to evaluate behavior and results of the prophylactic antimicrobial therapy in patients treated in a basic working group. Method: a descriptive observational study was conducted with 93 patients who were applied prophylactic antimicrobial therapy in the University Hospital Manuel Ascunce Domenech from December 2009 to July 2010. Results: the average age was 43,5 years. A relationship between the sexes was about 2 to 1,4. The method was applied mostly in 28 patients with closed fractures which internal fixation was made. The cefazolin was the most used in 70,9 % of patients. Thirty-five patients showed one or more risk factors closely associated with infection, of them one suffered postoperative infection. Adverse reactions were found in 4.3 % of patients. Conclusions: prophylactic antimicrobial therapy is effective in the prevention of postoperative infection.

Keywords : PRODUCTS WITH ANTIMICROBIAL ACTION; ANTIBIOTIC PROPHYLAXIS; EPIDEMIOLOGY, DESCRIPTIVE; SURGICAL WOUND INFECTION [therapy].

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