BUENO RODRIGUEZ, José Carlos. Economic impact of the sequential use of antimicrobials in children with complicated acute appendicitis. []. , 19, 1, pp. 26-33. ISSN 1025-0255.

Background: the present study demonstrates the economic results achieved with the sequential application of antimicrobials in children treated because of complicated acute appendicitis in the pediatric surgery department of Camagüey. Method: a transversal quasi-experimental study was conducted in all the cases of children treated because of complicated acute appendicitis between January, 2010 and December, 2013 in the pediatric surgery department of the Eduardo Agramonte Piña Pediatric Teaching Hospital of Camagüey. The economic results were compared to those obtained from the patients treated because of the same disease between January, 2006 and December, 2009. Results: four hundred and one patients were included in the study. Between the years 2006-2009 the hospital stay was of 7, 03 days/ patient; on the other hand, between the years 2010-2013 it was of 4, 02 days/patient. On average, the cost per patient was $ 578, 8 for the cases and $ 953, 6 for the controls. The consumption of antimicrobials, between 2006 and 2009, was of 3 755 ampoules of ceftriaxone, 2 253 ampoules of amikacin and 4 506 bottles of metronidazole; between 2010 and 2013 only 1 965 ampules of ceftriaxone, 1 179 ampoules of amikacine and 2 358 bottles of metronidazole were used. Conclusions: the study demonstrated a notable reduction in hospital stay and costs and in the use of expensive antimicrobials.

: APPENDICITIS [complications]; ANTI-INFECTIVE AGENTS [economics]; ENVIRONMENTAL IMPACT; EPIDEMIOLOGY, EXPERIMENTAL; CHILD.

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