Resumen

GONZALEZ RODRIGUEZ, Raidel; CARDENTEY GARCIA, Juan  y  CASANOVA MORENO, María de la Caridad. Results of Heberprot-p® in patients with diabetic foot ulcers. AMC [online]. 2015, vol.19, n.4, pp.366-374. ISSN 1025-0255.

Background: diabetic foot syndrome is one of the chronic complications that cause more morbidity and disability in diabetic patients nowadays. High amputation rates cause a significant degree of disability along with a high social and economic cost. It has been showed that the use of Heberprot-p® stimulates granulation tissue formation in the ulcer bed and the closing by second intention. Objective: to describe the results of Heberprot-P® in patients with diabetic foot ulcers in Raúl Sánchez Policlinic, Pinar de Río. Methods: a descriptive, prospective study of 23 patients with the diagnosis of diabetic foot ulcer was conducted from January 2014 to February 2015 in Raúl Sánchez Policlinic, Pinar del Río. The patients were applied epidermal growth factor intralesionally. The patients were studied taking into account age, sex, personal-pathological history, severity degree according to Wagner’s classification, the dose and the number of applications, the evaluation of the response and the side effects. Results: patients aged between 50 and 59 (47, 8 %) predominated in the studied series, as well as female sex (60, 9 %) and diabetes mellitus type II. The greater number of applications was in plantar ulcers degree II. A whole granulation was achieved in the 78, 2 % of the cases and a partial granulation in the 17, 3 %. There was not need of amputations and none of the patients died. Conclusions: with the use of Heberprot-P®, a favorable evolution has been achieved in most of the cases and the integrity of the limb has been kept as well as its function in most of the patients.

Palabras clave : DIABETIC FOOT [complications]; TREATMENT OUTCOME; EPIDERMAL GROWTH FACTOR; DRUG EVALUATION; EPIDEMIOLOGY, DESCRIPTIVE.

        · resumen en Español     · texto en Español     · Español ( pdf )