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Revista Archivo Médico de Camagüey

On-line version ISSN 1025-0255

Abstract

GONZALEZ RODRIGUEZ, Raidel; CARDENTEY GARCIA, Juan  and  CASANOVA MORENO, María de la Caridad. Results of Heberprot-P® in patients with diabetic foot ulcers. AMC [online]. 2015, vol.19, n.6, pp.590-598. ISSN 1025-0255.

Background: diabetic foot syndrome is one of the chronic complications that cause more morbidity and disability in diabetic patients, nowadays. The high amputation rates cause a significant degree of disablement with high economic and social costs. It has been proved that the administration of Heberprot-P® stimulates the granulation tissue formation in the bed of the wounds, as well as the secondary intention closure. Objective: to describe the results of Heberprot-P® in patients with diabetic foot ulcers in Raúl Sánchez Policlinic in Pinar del Río municipality, Pinar del Río. Methods: a descriptive, prospective study was conducted in 23 patients with the diagnosis of diabetic foot ulcer. The study was carried out from January, 2014 to February, 2015 in Raúl Sánchez Policlinic. The patients underwent an intralesional treatment with epidermal growth. They were studied taking into account their age, sex, personal pathological history, severity degree according to Wagner's classification, the doses and number of applications, the evaluation of the response and the side effects. Results: patients between 50 and 59 years old (47, 8 %) predominated in the group studied, as well as female sex and diabetes mellitus type II. The cases with II degree plantar ulcers received the greatest number of applications of the medicine. A full granulation was achieved in the 78, 2 % of the cases and a partial granulation in the 17, 3 %. There was not need of amputations and none of the patients died. Conclusions: with the use of Heberprot-P®, a favorable evolution was achieved in most of the cases. The integrity of the limb and its function could be kept in most of the patients.

Keywords : DIABETIC FOOT; TREATMENT OUTCOME; ULCER; RISK FACTORS; EPIDEMIOLOGY, DESCRIPTIVE.

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