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Revista Archivo Médico de Camagüey

versión On-line ISSN 1025-0255


HERNANDEZ GONZALEZ, Erick Héctor; MOSQUERA BETANCOURT, Gretel  y  RONDON MARTINEZ, Evarelis. Malignant pleomorphic storiform fibrous histiocytoma of the left arm. AMC [online]. 2017, vol.21, n.3, pp.370-377. ISSN 1025-0255.

Background: malignant fibrous histiocytoma is the most frequent soft tissue sarcoma in adulthood. It is seen in extremities in about 70-75 % and lower limbs are the most affected ones with 60 %. Objective: to present a case of malignant storiform pleomorphic histiocitoma of the left arm who underwent surgical treatment at universitary hospital Manuel Ascunce Domenech of Camagüey in 2016. Clinical case: a 60 year old male patient with a round increasing volume in posterolateral proximal left arm with collateral circulation. It was palpated a 20 cm diameter smooth, firm, fix to deep planes and painful mass with negative auscultation. Simple left humerus radiography informed a homogeneous radiopacity in surrounding soft tissues, no periosteal reaction or bone damage. Ecography of soft tissues: hypoecoic image of 200 x 170 mm between triceps and deltoid muscles reaction, with well defined pseudocapsule and no bone affection. An aspiration biopsy was done which inform a malignant mesenchimal neoplasia as a possible malignant histiocytoma. Surgical treatment was carried out to remove the tumor with oncologic margins. Final biopsy after immunohystochemical staining revealed a malignant fibrous pleomorphic storiform histiocytoma. The patient was sent to oncologic treatment with radiotherapy and a local recurrence was diagnosed, that is why a four quarter amputation was achieved. Conclusions: malignant fibrous histiocytoma is the most frequent soft tissue sarcoma in adulthood. There are different histological varieties, that is why immunohystochemical staining is a key tool for accurate diagnosis. Surgery and radiotherapy are the best therapeutic combination. Age, tumor depth, histological variety, location, absence of metastasis and size are the most important prognosis factors.


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