SciELO - Scientific Electronic Library Online

 
vol.24 issue6Diaphyseal distal third tibial fracturesOral cavity as a transmission source for SARSCoV-2 author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista Archivo Médico de Camagüey

On-line version ISSN 1025-0255

Abstract

PIAMO-MORALES, Alberto José; GARCIA-ROJAS, Mayra; GARCIA-ROJAS, Milagros  and  CAMPO-BEROES, Omar. Autopsy findings in COVID-19 Infection. AMC [online]. 2020, vol.24, n.6, e7572.  Epub Dec 01, 2020. ISSN 1025-0255.

Background:

COVID-19 pneumonia is a recently recognized disease that has spread rapidly throughout the world. The pathogenic foundations and histopathological changes caused by COVID-19 are not fully understood, which undermines the proper clinical identification of patients and the implementation of effective therapeutic strategies.

Objective:

to describe the histopathological findings found at autopsy of confirmed cases of COVID-19.

Methods:

evidence was collected by searching PubMed for English language publications, using the keywords: coronavirus, COVID-19, autopsy and acute respiratory distress syndrome in various combinations in 2020. Only five articles were found with information on the autopsy results of confirmed cases with COVID-19.

Results:

since the start of the pandemic in December 2019, seven autopsy reports of confirmed cases with COVID-19 have been published, collected in 4 articles. All autopsies have agreed on the main finding: diffuse alveolar damage with hyaline membrane formation, which correlates with the clinical manifestations of acute respiratory distress syndrome.

Conclusions:

COVID-19 mainly produces alveolar damage, which consists of pulmonary edema with hyaline membrane formation, which is clinically expressed as an acute respiratory distress syndrome.

Keywords : RESPIRATORY DISTRESS SYNDROME, ADULT/complications; CORONAVIRUS INFECTIONS/pathology; PULMONARY EDEMA/etiology; HYALINE MEMBRANE DISEASE; AUTOPSY.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )