Background:

the recurrent wheeze is the presence of the three or more episodes of wheeze and it is the main manifestation of asthma in children under five years old.

Objective:

to determine no atopic factors associated with recurrent wheeze in children less than five years.

Methods:

an analytic observational retrospective case-control study was made in Guáimaro, Camagüey province, Cuba from June 2017 to January 2020. The cases were 114 children under five years old with diagnostic of recurrent wheeze and the same number of children without diagnostic of recurrent wheeze was the controls. The information was obtained through a questionnaire applied to parents of children. The variables analyzed were: exclusive breast-feeding for less than six months, start of the complementary nutrition before six months, introduction of egg and or fish before six months, junk food before six months, obesity, smoker mother in pregnancy, cohabitation with smokers, indoor cohabitation with dog or cat, bronchiolitis history, history of recurrent low respiratory infections, intestinal parasitism and reiterated treatment with anti-bacterial. Data were computerized in SPSS 25 version.

Results:

cohabitation with smokers exclusive breast-feeding for less than six months, bronchiolitis history, smoker mother in pregnancy and obesity showed significant associations with recurrent wheeze.

Conclusions:

the no atopic risk factors for recurrent wheeze were: cohabitation with smokers, exclusive breast-feeding for less than six months, bronchiolitis history, smoker mother in pregnancy, obesity.

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