SciELO - Scientific Electronic Library Online

 
vol.21 número3Caracterización de aislamientos clínicos de Leptospira por métodos fenotípicos y moleculares en la República de NicaraguaLa gD2 coadministrada con el AFCo1 por vía intranasal induce inmunidad protectora contra virus de herpes simple tipo 2 en ratones índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

  • No hay articulos citadosCitado por SciELO

Links relacionados

  • No hay articulos similaresSimilares en SciELO

Compartir


Vaccimonitor

versión impresa ISSN 1025-028X

Resumen

ALVAREZ, Mirta et al. Prescription and surveillance of the sublingual immunotherapy with standardized domestic mite vaccines in allergology service. Vaccimonitor [online]. 2012, vol.21, n.3, pp.13-18. ISSN 1025-028X.

Allergen-specific immunotherapy consists of administering gradually increasing doses of the allergen, to which the patient is sensitized, aiming at achieving tolerance to it and decreasing clinical symptoms. The sublingual immunotherapy (SLIT) was introduced as an alternative to subcutaneous route. The objective was to assess the safety of sublingual standardized vaccines of three domestic mite species (VALERGEN, Cuba) and its adverse events in allergic patients from the Calixto García University Hospital in Havana, as well as the frequency of the vaccine prescription. A descriptive and cross sectional study design included 130 patients with treatment of SLIT with VALERGEN (BIOCEN, Cuba), who attended the Allergy Service in the period from January to September 2010. Age distribution: mean 19.6 years (range 1-75), 40.7% was younger than 18 years. The multiallergen vaccine was the most used (63.8%). The most common allergen was D. pteronyssinus followed by B. tropicalis . 71.55% of administered allergens vaccines were in maintenance phase. We found 4 adverse events (3.1% of patients), all local, mild, and not requiring treatment or change of dosing schedule. The VALERGEN vaccines by sublingual route were shown to be safe and well tolerated in Cuban allergic patients.

Palabras clave : Immunotherapy; sublingual vaccines; adverse events; VALERGEN; allergy.

        · resumen en Español     · texto en Español     · Español ( pdf )