Abstract

RODRIGUEZ-SANTOS, Olimpio  and  DEL VALLE-MONTEAGUDO, Nancy. Immunotherapy with industrial extracts of house mites in children under 5 years old with rhinitis and asthma. Vaccimonitor [online]. 2018, vol.27, n.2, pp.61-66. ISSN 1025-028X.

Sublingual immunotherapy (SLIT) is used in children for its safety, although there are some disagreements regarding the age of application. In order to study this treatment in depth, a study was conducted in children from 6 months to 5 years old in the health area of Previsora Camagüey, Cuba. The sample was taken in the children population with rhinitis, asthma and personal and family history of atopy. The study group, those treated in the Allergology service with positive skin prick test (SPT) to mites: Dermatophagoides pteronyssinus (Dp), Dermatophagoides siboney (Ds) and Blomia tropicalis (Bt) and SLIT to these mites. Children not treated by the Allergology service were the control group. In both groups, emergency attendance, hospital admissions, drug consumption were recorded, as well as the RQLQm and Juniper AQLQm questionnaires, at the beginning of the study and after 15 years of follow-up. The positive SPT were higher in allergic rhinitis, both children under 2 years and 2 to 5 years old. No statistical significance was found between these age groups. Allergic sensitivity was mainly found to Dp+Ds+Bt, with percentages higher than 50%. The attendance to emergency services and hospital admissions in the study group was lower than in the control, as well as the drug consumption. The quality of life score was higher in the study group. Children under 5 years old with SLIT are less likely to consume medications, to attend the emergency room and hospitalization, and their quality of life is superior to controls

Keywords : immunotherapy; mites; rhinitis; asthma.

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