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Revista Cubana de Plantas Medicinales
versión On-line ISSN 1028-4796
Resumen
MARTINEZ GUERRA, María Julia et al. Evaluación toxicológica aguda de los extractos fluidos al 30 y 80 % de cymbopogon citratus (D.C.) stapf (caña santa). Rev Cubana Plant Med [online]. 2000, vol.5, n.3, pp. 97-101. ISSN 1028-4796.
The acute toxicologic evaluation of the fluid extracts 30 and 80 % of Cymbopogon citratus (D.C.) Stapf (lemon grass), a plant used for its anticatarrhal, antiasthmatic, diuretic and antitussive effect and to control the arterial pressure was made. It was shown that the manifestations of toxicity are more evident as the concentration of fluid is higher. These manifestations were more probable among the animals treated with fluid extract 80 %. It was observed that the damages centered in the stomach with mild vascular congestion and focal hemorrhagic infiltrate in the lamina propia, liver and kidney, where the histological findings allow to confirm the hepatotoxic and nephrotoxic effect of these fluid extracts.
Palabras clave : PLANTS, MEDICINAL [toxicity]; PLANT EXTRACTS [toxicity]; ANIMALS, LABORATORY; MICE; MEDICINE, HERBAL.