Revista Cubana de Plantas Medicinales
versión On-line ISSN 1028-4796
APECECHEA COFFIGNI, Martha R et al. Actividad anticoagulante in vivo del extracto acuoso de las hojas de Ricinus communis. Rev Cubana Plant Med [online]. 2002, vol.7, n.3, pp. 0-0. ISSN 1028-4796.
A pharmacological study of anticoagulant effect of 3 % total solid - concentration of aqueous extract of Ricinus communis leaves was made. The study was performed in 1,5 -3 kg body weight New Zealand -line rabbits. Blood sample was taken directly from heart muscle, central vein of ear and carotid artery after administration of 2,0 mg/kg weight dose of extract injection into intravenous bolus through marginal ear vein. Protrombine time, Activated Thromboplastine partial time and Howell´time test were performed. The injection of extract into intravenous bolus increased studied coagulation times.
Palabras llave : RICINUS COMMUNIS; ANTICOAGULANTS.