Resumo

CASTELLANOS PUERTO, Edelis; PEREZ DE ALEJO, José Luis  e  MACHIN LUGONES, Maribel. Efecto antiviral de tinturas de Hypericum spp. cultivadas en Cuba. Rev Cubana Plant Med [online]. 2002, vol.7, n.3. ISSN 1028-4796.

A study in vitro was made to demonstrate the antiretroviral activity of 2 Hypericum species obtained in Cuba (fasciculatum and styphelioids). Hepatitis b virus surface antigen (HbsAg) was used and mixed with both species at concentrations of 1,5,10,20and 30mg/mL and then incubated at 24h, 48h, 72h and 7d, 14d and 21d. Then the reduction of antigenicity in vitro was evaluated by a sandwich-type immunoenzymagtic assay ELISA that quantifies HbsAg. It was observed that antigenicity decreased at 24 h for all the tested concentrations; however, from 72h on, a significant reduction of antigenicity occurred at Ag concentrations below the limit values recorded for ELISA tests performed. This study represents a possibility to be used for HbsAg and in HIV treatment.

Palavras-chave : PLANTS, MEDICINAL [chemical]; ANTIVIRAL AGENTS; HEPATITIS B SURFACE ANTIGENS.

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