Abstract

BLANCO HERNANDEZ, Neylim; RAMOS RUIZ, Alberto  and  VIZOSO PARRA, Ángel. Toxic and genotoxic assessment of fluid extract from Piper auritum H.B.K. Rev Cubana Plant Med [online]. 2006, vol.11, n.3-4. ISSN 1028-4796.

The acute toxicity of fluid extract from Piper auritum H.B.K. as well as its genotoxic activity were evaluated through two short term assay systems, one in vitro using the D-30 strain of Aspergillus nidulans and, another in vivo, the micronuclei assay in mouse bone marrow. The results allow to conclude that the fluid extract from P.auritum H.B.K. showed a very low acute toxicity and that it proved to be genotoxic in vitro but not in vivo .

Keywords : Piper auritum H.B.K; caisimon de anís; Aspergillus nidulans; micronuclei assays; acute toxicity; genotoxicity..