Resumo

TILLAN CAPO, Juana; NUNEZ FIGUEREDO, Yanier; AGUERO FERNANDEZ, Sara  e  CARRILLO DOMINGUEZ, Carmen. Anti-inflammatory activity of liposoluble compounds of Zingiber officinale Roscoe versus different inflammatory agents. Rev Cubana Plant Med [online]. 2007, vol.12, n.2. ISSN 1028-4796.

There is a background for use of oily extract with purified butter of Zingiber officinale Roscoe in treatment of allergic diseases and of airways by Mexican people; also, tasks performed in our lab demonstrated a protective effect of it in case of bronchospasm provoked by hystamines, and in experimental cutaneous passive anaphylaxis. Since these results anti-inflammatory assessment of such extract was made in induction models of plantar edema in rat, using different flogistic agents as Dextran, Histamine, Serotonine, and Carragenine. Rats received oleic extract of Zingiber officinale Roscoe by oral route, at a dosis of 6,5 mL/kg of body weight, one hour before induction of plantar edema, also we assessed Cyproheptadine, Diphenhydramine and Indomethacin as positive controls. Statistical analysis showed that administration of oleic extract of Zingiber officinalie Roscoe produces a significant inhibition (p < 0,05) of edema development induced by Dextran, Histamine, Serotonine, and Carragenine.

Palavras-chave : Zingiber officinale Roscoe,; anti-inflammatory model; inflammatory agents; rats; oleic extract..