Resumo

TILLAN CAPO, Juana et al. Effect of the water extract from Aloe vera (L.) N. L. Burm. on rabbit serum lipids. Rev Cubana Plant Med [online]. 2008, vol.13, n.4. ISSN 1028-4796.

INTRODUCTION: the research works conducted with water extract and gel from Aloe vera (L.) N. L. Burm., administered to mice in a triton-induced acute hyperlipidemia pattern, showed a protective effect against the increase of lipids. OBJETIVES: to study the effect of administration of water extract from A. vera at repeated doses on the lipid indicators of rabbit serum. METHODS: male New Zealand rabbits were treated with water extracts from Aloe vera at doses of 17 and 34 mg/kg of bodyweight, on the basis of whole solids for 6 weeks. An untreated control group was included. Body weight, total cholesterol, HDL-cholesterol, LDL cholesterol and triglycerides were determined at the beginning and at the end of the experimental period. RESULTS: it was found that cholesterol, LDL cholesterol and triglycerides significantly decreased in serum of animals treated with 34 mg/kg dose of the water extract at the end of the experiment, however, the HDL-cholesterol did not show any variation. CONCLUSIONS: the administration of water extract from Aloe vera to a rabbit for 6 weeks significantly reduced serum lipids.

Palavras-chave : Aloe vera; water extracts; cholesterol; LDL-cholesterol, triglycerides; rabbits.