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Revista Cubana de Plantas Medicinales
versão On-line ISSN 1028-4796
Resumo
DE LA PAZ MARTIN-VIANA, Nilia et al. Technological development of a sedative medicine of natural origin from Justicia pectoralis Jacq. Rev Cubana Plant Med [online]. 2011, vol.16, n.3, pp. 227-235. ISSN 1028-4796.
Introduction: the use of natural raw materials as active ingredient is increasingly spreading in the drug industry for the manufacture of pharmaceuticals. Justicia pectoralis Jacq.(Acantaceae) is a herbaceous plant traditionally used as sedative by the Cuban population which knows it as lime tea. Objective: to develop syrup containing the dry extract from J. pectoralis 0.6 % m/v as active principle. Methods: the formulation, microbiological and chemical/physical stability studies were performed on the product stored at room temperature in 125 mL amber-coloured glass containers. Results: the syrup had adequate organoleptic characteristics and was stable from the microbiological, physical and chemical viewpoints for 36 months under the studied conditions. Conclusions: this pharmaceutical was properly formulated from the galenic viewpoint and met all the set quality requirements for this type of pharmaceutical form.
Palavras-chave : stability; Justicia pectoralis Jacq; syrup; natural product; phytopharmaceutical; sedative.