Abstract

CABRERA SUAREZ, Hirán; CUELLAR CUELLAR, Armando  and  PITA, Roberto Carlo. Characterization of cycloartanol triterpene isolated from dichloromethane extract of Pedilanthus tithymaloides. Rev Cubana Plant Med [online]. 2011, vol.16, n.4, pp. 347-353. ISSN 1028-4796.

Introduction: Pedilanthus tithymaloides is known as ítamo real and it has been previously reported as an alternative to treatment of oral cavity virus infections. Objective: to explain procedures to characterize one of the major compounds isolated from dichloromethane extracts of Pedilanthus tithymaloides (L.) Poit (leaves). Methods: it was obtained cycloartanol from dichloromethane extract modifying polarity of the solvents with methanol and by increasing polarity to extract, they were used chromatography technique and spectroscopic of nuclear magnetic resonance H⁺ and ¹³C to characterize this compounds. Results: phytochemical studies showed quality parameters that were similar to average limits in the use of majority of medicinal plants except total ashes assay (13 %), qualitative determination assay suggest presence of reducers compounds, quinone, phenols and/or tannins, triterpene and/or steroids. And they were compared spectrum carbon 13 (¹³C) of the substance obtained from extract of this plant with other reported in literature to cycloartanol and found coincidence in majority of carbons compared. Conclusions: cycloartanol triterpene was one of main compounds of dichloromethane extract of Pedilanthus tithymaloides (L) Poit leaves.

Keywords : Pedilanthus tithymaloides; Cycloartanol; Triterpene; Itamo real; Phytochemistry.