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Multimed
versión On-line ISSN 1028-4818
Resumen
PEREZ DOMINGUEZ, Julio Alberto et al. Prognostic evaluation of acute coronary syndrome in patients with metabolic syndrome. Multimed [online]. 2019, vol.23, n.4, pp. 685-698. ISSN 1028-4818.
Introduction:
metabolic syndrome increases the risk for cardiovascular disease and doubles mortality.
Objective:
to identify the prognostic factors of death due to acute coronary syndrome in patients with metabolic syndrome.
Method:
a cohort analytical observational study was conducted in 186 patients with acute coronary syndrome admitted between 01 February 2015 and 20 October 2018. Clinical and epidemiological variables were included; the strength of association between the qualitative variables and the risk of developing death due to acute coronary syndrome in the presence of metabolic syndrome with Odds Ratio with 95% confidence interval was evaluated. Multivariate analysis was performed using the Cox logistic regression model.
Results:
the prevalence of the metabolic syndrome was 45.7%, with a mean age of 60.6 years; Female sex and age group over 61 years doubled the risk in a non-significant way. Left ventricular hypertrophy, heart failure and atrial fibrillation increased the risk of the appearance of a statistically significant acute coronary syndrome in the presence of the metabolic syndrome, p, 000. Moderate to severe left ventricular dysfunction [OR 5.7 95% CI (1,115-5,961) p, 000], Killip-Kimball class ≥II [OR 7.9 IC 95% (3, 10-20, 15) p, 000] and infarction without ST elevation [OR 2.970 95% CI (1.174-7.518) p, 000], were significantly related to death.
Conclusions:
metabolic syndrome increases the risk of suffering acute coronary syndrome and death but it is not significantly related to survival.
Palabras clave : Acute Coronary Syndrom; Metabolic Syndrome.