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versión On-line ISSN 1028-4818


FERRER MONTOYA, Rafael et al. Maternal and neonatal risk factors for early-onset infection proven in the preterm term. Multimed [online]. 2020, vol.24, n.5, pp.1163-1182.  Epub 17-Sep-2020. ISSN 1028-4818.


Neonatal infection is a clinical syndrome that constitutes an important cause of neonatal morbidity and mortality.


to determine the relationship between some maternal and neonatal factors and the occurrence of early-onset infections tested in the neonatology service of the General University Teaching Hospital Carlos M. de Céspedes in the period from January 2014 to December 2019.


an analytical investigation of cases and controls was carried out whose sample consisted of 450 neonates diagnosed with proven early infection and 900 controls with a ratio of 1 case to 2 controls.


in relation to maternal variables, the age of the mother, with O.R 1.74, an IC. 95% (1.28-2.34) with p:0.003, the gestational age less than 31 weeks an O.R: 2.14, and a p: 0.006, vaginal infection an OR: 5.19, and p: 0.000, urinary infection OR: 4.99, and p: 0.000; dystocic delivery as a risk factor an OR: 0.98 y p: 0.923, the rest of the maternal variables such as membrane rupture time greater than 18 hours, abnormal amniotic fluid (fetid and / or purulent), the total time of prolonged labor and the politact p <0.05; clinical and histological chorioamnionitis with p <0.05; the weight of the neonate less than 1000 grams and 1000-1499 grams with p: 0.004 and 0.02 respectively, the male sex with OR: 1.82 and p: 0.000 and the Apgar score less than 7 at the first and fifth minute of life p <0.05.


the maternal variables except dystocic delivery were significant, and the neonatal variables studied were significant.

Palabras clave : Maternal and neonatal risk factors; Early neonatal infection; Newborn; Proven infection.

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