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Revista Información Científica
versión On-line ISSN 1028-9933
Resumen
ALI PEREZ, Niurka Aurora; MATOS BAYEAU, Ariel Arturo y RODRIGUEZ RUIZ, Marlene. Delayed hemolytic transfusion reaction by anti-E alloantibody. Rev. inf. cient. [online]. 2019, vol.98, n.1, pp. 98-105. ISSN 1028-9933.
We present the case of a 47-year-old woman, blood group O Rh D positive, G4P2A2, with no transfusion history, which required surgical intervention due to bleeding uterine fibroma. The pretransfusional tests were compatible, transfusing two concentrates of red blood cells, without presenting clinical manifestations; After seven days, he presented a haemolytic crisis, with abrupt fall in hematological parameters, cutaneous-mucosal pallor and icterus. The immunohematological studies were positive; the patient's blood sample was incompatible with a son, husband and the transfused red blood cells. Six months later, an anti-E alloantibody (128 dilutions) was identified in the patient. It is concluded that the patient was alloimmunized during her pregnancies with an anti-E antibody, where the blood transfusion was the antigenic stimulus causing the late hemolytic transfusion reaction.
Palabras clave : alloantibody; sensitization; blood transfusion; delayed hemolytic transfusion reaction.