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MEDISAN

On-line version ISSN 1029-3019

Abstract

NUNEZ COPO, Antonio César  and  RODRIGUEZ CHANG, Juan Carlos. Characterization of twins with schizophrenia in the municipality of Santiago de Cuba. MEDISAN [online]. 2010, vol.14, n.1. ISSN 1029-3019.

A descriptive and cross-sectional study was conducted in 24 pairs of twins diagnosed with schizophrenia, irrespective of their zygosity, in Santiago de Cuba municipality from February to April, 2007, selected by means of a simple random sampling to characterize them. It was mainly observed that the average age of symptom onset was lower in monozygotic twins and prenatal history increased the risk of disease. The presence of family history was verified, with a predominance of first-degree relatives. There was a higher frequency of concordance between monozygotic twins, as well as a high percentage of heritability.

Keywords : twins; zygosity; schizophrenia; concordant monozygotic; concordant dizygotic; heritability.

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