Abstract

NAPOLES MENDEZ, Danilo  and  COUTO NUNEZ, Dayana. Venous thromboembolic disease in pregnancy and puerperium. Part 2: Prevention and treatment. MEDISAN [online]. 2011, vol.15, n.11, pp.1577-1597. ISSN 1029-3019.

Venous thromboembolic disease is an important cause of morbidity and mortality in the pregnant-puerperal period, which has given rise to multiple controversies regarding its prevention and treatment. This article outlines the preventive measures and therapies to treat women with thromboembolic disease in pregnancy and puerperium, for which the general measures and the use of antithrombotics in the prophylaxis of this condition are detailed, as well as their use for therapeutics. New anticoagulants, direct thrombin inhibitors and Anti/Xa are described and the surgical treatment modalities are presented as well, allowing as a result to introduce a care protocol for treatment of these patients. It is concluded that although the risk population prophylaxis is the cornerstone of prevention, effective anticoagulation is the basic tool to reduce the mortality.

Keywords : venous thromboembolic disease; risk population; prophylaxis; anticoagulation; pregnancy; puerperium.

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