Abstract

ESTRADA PEREIRA, Gladys Aída; MARQUEZ FILIU, Maricel; HERNANDEZ ALVAREZ, Galina  and  OLIVEROS NORIEGA-ROLDAN, Silvana. Identification of the human papilomavirus in oral leukoplakia. MEDISAN [online]. 2013, vol.17, n.6, pp.944-950. ISSN 1029-3019.

With the purpose of evaluating the results of the clinical and histopathological diagnosis of the human papilomavirus associated with oral leukoplakia, a descriptive and cross-sectional study was carried out in 75 patients with this condition, who were treated at the Stomatology Department of the Polyclinic of Specialties from "Saturnino Lora" Provincial Teaching Clinical Surgical Hospital of Santiago de Cuba, from September 2009 to the same month of 2012. Biopsies were taken from patients to detect the presence of koilocytes producing chorion and epithelial changes in damaged tissue, as well as their topographic location. Male sex, buccal mucosa as the anatomical site of highest incidence and epithelial dysplasia as the most significant prevailed in the case material. Likewise, the loss of the nuclear-cytoplasmic ratio and hyperplasia of the basal layer were the most frequent tissue alterations.

Keywords : human papilomavirus; oral leukoplakia; histopathological diagnosis; biopsy; koilocytes; epithelial dysplasia; secondary health care.

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