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MEDISAN
On-line version ISSN 1029-3019
Abstract
CLAVERIA CLARK, Rafael Alberto; RODRIGUEZ GUERRERO, Katiuska and PENA SISTO, Maritza. Clinical, genetical and epidemiological characteristics of the epidermolysis bullosa and its influence in the oral cavity. MEDISAN [online]. 2015, vol.19, n.8, pp.995-1005. ISSN 1029-3019.
The epidermolysis bullosa is an infrequent disorder, with a prevalence of 0,5 - 1 per million of inhabitants comprising a group of genetic changes characterized by bullous lesions in the skin and mucosa, which diagnosis requires of the use of molecular biology and inmunohistochemical techniques. For such effects, an exhaustive review was carried out with the aim of deepening in the clinical, genetic and epidemiological characteristics of this disease and its influence on the oral cavity, as well as in some punctual aspects related to the topic
Keywords : epidermolysis bullosa; genetic change; blistering lesion; epidermis; dermis; oral mucosa.