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MEDISAN
On-line version ISSN 1029-3019
Abstract
LEMUS RODRIGUEZ, Martha Zoe; CHONG QUESADA, Amaury and BOSCH ESCOBAR, Jorge. Chewable pill of soy phosphatidylcholine: from by-product to pharmaceutical product. MEDISAN [online]. 2017, vol.21, n.5, pp.556-563. ISSN 1029-3019.
The development of a chewable pill of soy phosphatidylcholilne was undertaken in "Oriente" Pharmaceutical Laboratory from Santiago de Cuba with registration ends and subsequent production, that was carried out during the biennium 2011-2013. Excipients of pharmaceutical quality, the analytic methods of the United States Pharmacopoeia, edition 35/National Form, 2012 30th edition, as well as the technology of humid granulation and direct compression were used. Phosphatidylcholine was characterized as pharmaceutical raw material and the developed pill fulfilled the established quality attributes, reason why it was registered with 2 years proven stability. Added value was given to this substance, with potential risk of accumulation for the environment, as new pharmaceutical product in Cuba
Keywords : phosphatidylcholine; chewable pill; soy; cholesterol; "Oriente" Pharmaceutical Laboratory.