Resumo

PEREZ LEYVA, Ernesto et al. Interferons Modern Therapeutic Option in the Treatment of Basal Cell Carcinomas. ccm [online]. 2016, vol.20, n.2, pp.275-291. ISSN 1560-4381.

Basocellular carcinoma is a skin malignant neoplasia that primarily affects white race  people. Potential carcinogenic effect is etiologically related to the accumulative explosion of ultraviolet rays, with the deterioration of the ozone layer this phenomenon tends to increase in the last few years, thus the search of efficacious and safe alternative treatments constitutes a health system priority. Interferons are biotechnological products known to modify the biological response that, due to its antiproliferative and antiantigenic properties, are employed in modern therapy of basothelioma. A revision was carried out in the main databases, choosing 46 articles that update the molecular aspects and the clinical trials that justify the use of immune therapy, and essentially, the interferons, as a safe and efficacious strategy in the treatment of this type of neoplasia.

Palavras-chave : basocellular carcinoma; interferons; therapy.

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