Abstract

LEGRA MATOS, Sara María et al. Oral Mucous Leukoplakia Follow up of Five Years in Patients of Holguín. ccm [online]. 2017, vol.21, n.3, pp.776-785. ISSN 1560-4381.

Introduction: leukoplakia of the buccal mucosa is a predominantly white lesion that cannot be characterized as any other well defined lesion and can be turn into cancer. Objective: to determine the relationship between age, sex, alcoholism and smoking as risk factors in the leukoplakia development. Methods: a cohort study was carried out with 129 patients whose definitive histopathological diagnosis was oral mucosal leukoplakia. The study was done between January 2009 and December 2014 at dental clinics from Holguín, Urbano Noris and Moa municipalities. Control cards and clinical histories were reviewed. After five years, 88 patients were reexamined. Results: there were 16 patients with recurrent leukoplakia on oral examination. The most affected group of 60 years old and over (11 patients) and the male sex with 13 individuals. There was a significant relationship between smoking and alcoholism and recurrent leukoplakia. The average risk to suffer from the disease is 3.44 (CI= 2.13 - 5.55) related to smoking, and 3.9 (CI = 2.34 - 6.48) related to alcoholism. Conclusions: the majority of male patients were from the age group of 60 years and over. There was a relevant relationship between smoking and alcoholism, as well as, the probability to have a recurrent lesion in patients with these habits.

Keywords : leukoplakia of the buccal mucosa; smoking; alcoholism; risk factors.

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