Resumen

PEREIRA ROCA, Giovanna et al. Immune cholesterol and coronary arteriosclerosis demonstrated by angiography. Rev Cubana Endocrinol [online]. 2001, vol.12, n.1. ISSN 1561-2953.

A descriptive and cross-sectional study was conducted to evaluate the levels of immune cholesterol. 102 patients who received attention at the Consulting Room of Ischemic Heart Disease of the National Institute of Cardiology and Cardiovascular Surgery during a year (no selection was made) were analyzed. These patients that apparently suffered from this disease underwent coronary angiography as part of the study in order to know the clinical usefulness of immune cholesterol as a diagnostic marker for coronary arteriosclerosis and to associate immune cholesterol with other lipid parameters. It was observed that the concentration of immune cholesterol was lower in apparently normal subjects than in patients with coronary arteriosclerosis and that among the latter it was higher in patients with degree 3 stenosis. It was proved that there is a positive association between the levels of immune cholesterol, total cholesterol and c-LDL in the serum of the studied patients and the degree of severity of the coronary arterial disease. No association was found between immune cholesterol and the rest of the lipid variables. Levels of "immune cholesterol" similar or higher than 17 µg/mL increase the risk for coronary arteriosclerosis from 1.3 to 8 times, being better predictors of the severity of the coronary lesion and of the presence of coronary arteriosclerosis than the most commonly known lipid risk markers.

Palabras clave : CHOLESTEROL; LIPOPROTEINS; LDL; CORONARY ARTERIOSCLEROSIS; CORONARY ANGIOGRAPHY.

        · resumen en Español     · texto en Español     · Español ( pdf )