Resumen

ACOSTA CEDENO, Alina; MONTEAGUDO PENA, Gilda  y  MENOCAL ALAYON, Ahmed. Hormonal pattern of women with clinical and echographic diagnosis of polycystic ovary syndrome. Rev Cubana Endocrinol [online]. 2004, vol.15, n.2. ISSN 1561-2953.

The polycystic ovary syndrome (POS) is a disorder of non well defined etiology with an aberrant hormonal pattern. The results of a descriptive cross-sectional study in which 30 women with clinical hyperandrogenism and at least 2 echographic elements suggestive of POS that were determined testosterone (T), androstenedione (Ad), dihydroepiandrosterone (DHEA) and its sulfate (DHEAs), follicle stimulating hormone (FSH) and luteinizing hormone (LH), were shown. Descriptive statiscians and Person's correlation test were used to analyze the results. The behavior of gonadotropins was very variable. The FSH was diminished in 3 cases, normal in 24 and increased in 3, with normal mean values (5.45 UI/L). The LH had values under the range of normality in 1 case, normal in 10 and high in 19, and an elevated mean value (12.49 UI/L). The ratio LH/FSH was over 3 in 14 patients (46.6 %). The mean values of all the androgens, excepting DHEAs were high; in 46.6 % of the cases it was found a rise of more than one androgen, and biochemical hyperandrogenism was not proved in 4 cases. The Ad and the DHEA were the most frequently rised androgens (50 % each one), followed by the T (30.0) and the DHEA (10.0). No correlation was observed among the studied variables. It was concluded that the association of clinical hyperandrogenism and echographic signs of POS did not guarantee uniformity in the hormonal behavior, so it is necessary to continue working to determine the diagnostic element that identifies the syndrome really.

Palabras clave : Polycystic ovary syndrome; reproductive hormones; hormonal pattern.