Revista Cubana de Endocrinología
versión On-line ISSN 1561-2953
OVIES CARBALLO, Gisel; DOMINGUEZ ALONSO, Emma; VERDEJA VARELA, Olga L y ZAMORA RECINOS, Hugo. Association among hormonal and clinical variables and the result of the gynecological ultrasound in females with metabolic syndrome.. Rev Cubana Endocrinol [online]. 2008, vol.19, n.2, pp. 0-0. ISSN 1561-2953.
OBJECTIVE: to determine the association between the result of the ultrasound and the progesterone values, LH/FSH level, testosterone, history of infertility and hirsutism in females with metabolic syndrome. METHODS: a descriptive cross-sectional study was undertaken among 90 females aged 18-45 with diagnosis of metabolic syndrome. FSH (3-5 days of the menstrual cycle), LH (3-5 days of the menstrual cycle), prolactin (3-5 days of the menstrual cycle), androgens (total testosterone, 3-5 days of the menstrual cycle), progesterone (21-23 days of the menstrual cycle) were determined if they were menstruating; otherwise they were established at any moment. A transvaginal gynecological ultrasound in the early follicular phase was performed if they had menstruation, but if they were amenorrheic it was carried out at any time. A medical history was also made to explore obstetric history, menstrual formula, history of infertility and physical examination. Associations between the clinical and hormonal variables and the ultrasonographic result were investigated. RESULTS: 83.1 % of the anovulatory showed images suggestive of ovarian polycystosis. When the testosterone levels were associated with the ultrasound, in 80 % of those who had an elevated testosterone, the ultrasound showed images of ovarian polycystosis; however, when testosterone was normal, just 42.5 % had such images. Of the 39 patients with an index ³ 2, 32 (82.1 %) presented an ultrasonographic image of ovarian polycystosis; however, when it was <2, only 49 % had them. 75 % of the females with infertility showed an ultrasound with signs of polycystic ovaries and 25 % did not. Of the 73 hirsute patients, 48 (65.8 %) had a positive ultrasound for ovarian polycystosis, whereas 25 (34.2 %) did not exhibit images suggestive of this disorder, without a significant difference. CONCLUSIONS: the association between anovulatory progesterone, elevated levels of testosterone, LH/FSH index ³ 2, infertility and hirsutism, with ultrasound images of polycystosis is very high in the studied women with metabolic syndrome.
Palabras llave : Ultrasound; hormones; infertility; hirsutism; metabolic syndrome.