Resumen

GONZALEZ RICARDO, Yaquelín; HERNANDEZ YERO, Arturo; DOMINGUEZ ALONSO, Emma  y  MACEO COELLO, Taira. Menstruation disorders and sexual hormones in women diagnosed with type 1 diabetes before menarche or after it. Rev Cubana Endocrinol [online]. 2010, vol.21, n.1, pp.51-61. ISSN 1561-2953.

INTRODUCTION: type 1 diabetes mellitus is a chronic disease frequent and frequent affecting the entire organism. Knowledge on gonadal axis function in diabetic persons nowadays has a great significance, not only due the repercussion of this disease in reproductive health. OBJECTIVE: to identify the menstrual irregularities frequency, to determine the sexual hormones levels and to establish the influence of this entity on the menarche age. METHODS: a cross-sectional descriptive study was conducted in 74 women aged 15 and 35, all seen in the Diabetes Care Center of Ciudad de La Habana, Cuba, which were distributed in two groups: A and B, both with n= 37; A: diagnosed with diabetes before the menarche appearance and B; after it. We designed a questionnaire of general data and puberal and menstrual medical records; we determined the presence of fasting glycemia, glycosylated hemoglobin and sexual hormones; both groups were compared using the t Student and chi² tests. RESULTS: we achieved a high frequency of dysmenorrhea, menorrhhea and premenstrual tension, as well the loss of a correlation among some sexual hormones. Earlier presence of type 1 diabetes mellitus determined a greater age of menarche, lower levels of gonadotropins (LH and FSH) and oligomenorrhea. CONCLUSIONS: type 1 diabetes mellitus diagnosed before menarche seems to interfere with maturation and subsequent function of female gonadal axis, which conditioned a greater frequency of dysmenorrhea and menstrual irregularities.

Palabras clave : type 1 diabetes mellitus; menstrual irregularities; and sexual hormones.

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