Resumen

PARLA SARDINAS, Judith et al. Frequency and characterization of metabolic syndrome according to the criteria of the International Federation of Diabetes in first degree relatives of persons with type 1 diabetes. Rev Cubana Endocrinol [online]. 2011, vol.22, n.3, pp. 196-209. ISSN 1561-2953.

Introduction: the metabolic syndrome is defined as the association of some factors causing cardiovascular disease and of type 2 diabetes mellitus. Objective: to determine the frequency of the metabolic syndrome according to the criteria of the International Federation of Diabetes in first degree relatives of persons with type 1diabetes. Methods: ninety six adults and 97 adolescents were selected to apply a questionnaire and a general physical examination. Also, assessment of fast glucose, insulin, cholesterol, triglycerides and HDL-cholesterol were carried out, estimating the rate of insulin-resistance. Results: the frequency of metabolic syndrome was higher in adults for a 17,7 % (17/96) than in adolescents for a 3,09 % (3/97) and the insulin resistance in adults was similar in those subjects with and without metabolic syndrome. The family history of cardiovascular disease, type 2 diabetes mellitus, obesity, dyslipemia and high blood pressure is not associated with the presence of metabolic syndrome in first degree relative of persons with type 1 diabetes. Conclusions: the metabolic syndrome, according the criteria of the International Federation of Diabetes, is more frequent in adult persons than in the adolescent first degree relatives of persons with type 1 diabetes and that the insulin resistance in these subjects is not exclusively associated with the metabolic syndrome.

Palabras clave : metabolic syndrome; insulin resistance; first degree relative of persons with type 1 diabetes.

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