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Revista Cubana de Endocrinología

versión On-line ISSN 1561-2953

Resumen

PARLA SARDINAS, Judith et al. Frequency and characterization of metabolic syndrome according to the criteria of the International Federation of Diabetes in first degree relatives of persons with type 1 diabetes. Rev Cubana Endocrinol [online]. 2011, vol.22, n.3, pp.196-209. ISSN 1561-2953.

Introduction: the metabolic syndrome is defined as the association of some factors causing cardiovascular disease and of type 2 diabetes mellitus. Objective: to determine the frequency of the metabolic syndrome according to the criteria of the International Federation of Diabetes in first degree relatives of persons with type 1diabetes. Methods: ninety six adults and 97 adolescents were selected to apply a questionnaire and a general physical examination. Also, assessment of fast glucose, insulin, cholesterol, triglycerides and HDL-cholesterol were carried out, estimating the rate of insulin-resistance. Results: the frequency of metabolic syndrome was higher in adults for a 17,7 % (17/96) than in adolescents for a 3,09 % (3/97) and the insulin resistance in adults was similar in those subjects with and without metabolic syndrome. The family history of cardiovascular disease, type 2 diabetes mellitus, obesity, dyslipemia and high blood pressure is not associated with the presence of metabolic syndrome in first degree relative of persons with type 1 diabetes. Conclusions: the metabolic syndrome, according the criteria of the International Federation of Diabetes, is more frequent in adult persons than in the adolescent first degree relatives of persons with type 1 diabetes and that the insulin resistance in these subjects is not exclusively associated with the metabolic syndrome.

Palabras clave : metabolic syndrome; insulin resistance; first degree relative of persons with type 1 diabetes.

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