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Revista Cubana de Endocrinología

versión On-line ISSN 1561-2953


DIAZ SOCORRO, Cossette et al. Modifiable or not factors related to mineral bone density in middle aged women. Rev Cubana Endocrinol [online]. 2012, vol.23, n.1, pp.44-55. ISSN 1561-2953.

Introduction: in Cuba there are not national data on the osteoporosis's prevalence. The world demographic changes make necessary the research and the diffusion of information relative to osteoporosis. Objective: to identify the possible differences in the bon mineral density, according to the presence of modifiable or not risk factors in middle aged women. Methods: a cross-sectional and descriptive study was conducted in 259 patients came to ClimOs consultation in the National Institute of Endocrinology ruled out the women presenting with secondary osteoporosis. The bone mineral density is determined by means of dual beam absorptiometry in distal forearm and lumbar spine. Patients were divided into two categories: those with a normal mineral bone density located in I group and those with a low bone mineral density (osteopenia and/or osteoporosis) corresponded to II group. To establish differences among groups the t student and chi2 tests with a 5 % significance level. The multiple logistic regression was used for analysis of bone mineral density integrating both study regions. Results: combining the results of the densitometry carried out in th forearm and lumbar spine of the 259 middle aged women, the 72.2 % had a low bone mass including 99 patients (38.2 %) with osteopenia and 88 (34.0 %) diagnosed with osteoporosis, only 72 (27.8 %) women had a normal bone mass. Applying the multiple logistic regression to statistically significant variables: age, skin color, family pathological background of fracture, ovarian function, body mass rate, follicle-stimulating hormone, luteinizing hormone and estradiol, those associated with a great probability to have a decreased bon mineral density were: white skin color (Odds Ratio= 3,949, p= 0,025), family background of fracture (Odds Ratio= 2,836, p= 0,044), and the post-menopause (Odds Ratio= 10,185, p= 0,008). Conclusions: the women middle aged with a great probability to have a decreased bone mineral density were those of white skin color, with family backgrounds of fracture and in those where the postmenopause is present.

Palabras clave : risk factors; bon mineral density; osteopenia; osteoporsis and densitometry.

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