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Revista Cubana de Endocrinología

versión On-line ISSN 1561-2953


MACIQUES RODRIGUEZ, Juana Elvira  y  CACERES TOLEDO, María. Thyroid orbitopathy. Rev Cubana Endocrinol [online]. 2012, vol.23, n.3, pp.225-233. ISSN 1561-2953.

Thyroid orbitopathy, also known as Graves' orbitopathy, is an inflammatory, autoimmune, and self-limiting disease that affects orbital and periorbital tissues. It is more frequent in women and linked to hyperthyroidism condition, although it may occur in hypothyroid and euthyroid patients, worsened by smoking and stress. It is mainly characterized by palpebral retraction and exophtalmos, but it may sometimes evolve into severe forms with significant impact on the vision due to compressive optic neuropathy or the loss of the eyeball integrity. The treatment ranges from simple protection of the eyeball in the milder forms, the use of glycocorticoids or other immunosuppressive drugs to the orbital decompression surgery in the most severe cases, which are increasingly less painful and more hopeful. This review was aimed at standardizing and updating the knowledge on this disease and at providing practical information for the early diagnosis and the adequate treatment of our patients.

Palabras clave : thyroid orbitopathy; Graves' orbitopathy; exophtalmos; orbital decompression.

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