Resumen

SALGADO BORGES, Mabel et al. Peridural morphine in cesarean section. Rev Ciencias Médicas [online]. 2005, vol.9, n.3, pp.21-30. ISSN 1561-3194.

Opioids are the most effective and frequently used drugs to relieve postoperative pain. In order to evaluate the effectiveness of administration of peridural morphine as an analgesic method in patients undergong cesarean section, the following prospective and ramdomized clinical trial was carried out with 200 patients with physical conditions ASA I y II distributed in four groups of 50 each, at Abel Santamaria Cuadrado Provincial Clicnical Teaching Hospital in Pinar del Rio from January, 2001 to January, 2004. All patients were given 2 % Lidocaine peridurally, according to recommendations by Morgan and Barash. Group I was only given the above mentioned local anesthesic without opiates. The other groups, II, III and IV were given the same anesthesic but with an addition of 1 mg, 2 mg, 3 mg morphine, respectively. After processing data an excellent analgesia was achieved in 100 % patients in groups III and IV. Group IV showed the highest incidence of hemodynamic changes (p < 0.05) and undesirable effects in mothers (p < 0.01); however, neonatal depression was not found in any groups. Doses of systemic analgesia or analgesic recovery were only necessary in groups I and II, 56.6 % and 44.4 %, respectively. The method used in group III showed best results providing for an excellent analgesia with minimal hemodynamic changes and undesirable effects.

Palabras clave : MORPHINE; CAESAREAN SECTION; PAIN.

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