Abstract

GUERRA PAREDES, Miriam; CAMACHO MACHIN, María Luisa  and  FORTUN PRIETO, Adalberto. Pulmonary function in patients suffering from sickle-cell anemia. Rev Ciencias Médicas [online]. 2005, vol.9, n.3, pp. 61-70. ISSN 1561-3194.

In order to assess the ventilatory capacity in patients with sickle cell anemia were selected and assisted at Leon Cuervo Rubio Provincial Hospital Hematology Department, from January - April 2003. The selection of patients was randomized. Along with the selection of clinical and hematological parameters obtained from the micro-histories made for the followup of patients; the patients were analyzed as for the lung performance. Results from ventilarory study were related to the selected variants using Microstat and applying chi ? square test. It was found all patients, exept one, presented ventilatory dysfunction, mostly restrictive. The obstructive component was present in 50 % cases, some of them as unique abnormality. There were no patients with chronic respiratory symptoms and the thoracic radiography was normal in all cases. There was no association between the typeof severity of the ventilatory dysfunction and the behaviour of the clinical and hematological variates evaluated. As a conclusion, the ventilatory repercussion in patients with sickle cell anemia must be taken into account even in the absence of clinical translation, and independently of the clinical and hematological behaviour of the disease.

Keywords : SICKLE CELL ANEMIA; VENTILATORY DYSFUNCTION.