Revista de Ciencias Médicas de Pinar del Río
versión On-line ISSN 1561-3194
QUINTERO PEREZ, William et al. Characterization of mononuclear cells in non- fertile men's sperm. Rev Ciencias Médicas [online]. 2007, vol.11, n.1, pp. 28-34. ISSN 1561-3194.
With the purpose of describing mononuclear-cell subpopulations existing innon-fertile men's sperm with leucoytospermia, a descriptive study was performed with 78 men members of infertile couples, with leucocytospermia, peroxidase-positive leucocytes greater than or equal to 1 x 106 leucocytes/ml., who attended the office of the National Endocrinology Institute (37) and the office of Abel Santamaría Cuadrado Hospital in Pinar del Río (41), 1999-2000. The study was carried out with antibodies which recognized different cellular particulars, such as macrofages, B cells, some activated T cells, all T lymphocytes, NK cells, CD8+ lymphocytes, CD4+ lymphocytes. The results were different from other revised studies, showing predominance of T cells and antigen-presenting cells. The presence of both types of cells suggesed the chances of establishing an inflammatory reaction with harmful cytocine release for the spermogram parameters, and the mobilisation of cells with the same effects, not quantified routinely. In different populations, where the prevalence of infections and toxic and irritant habits causing leucoytospermia are very different, much difference can be seen in sperm cellular patterns.
Palabras llave : INFERTILITY; prevalence; epidemiology.