Abstract

CIRION MARTINEZ, Gladys R  and  HERRERA PEREZ, Miguel Angel. Histopathology of Chronic Viral Hepatitis-C, Pinar del Rio. January 2002- July 2008. Rev Ciencias Médicas [online]. 2009, vol.13, n.4, pp.49-61. ISSN 1561-3194.

Despite being hepatitis caused by C virus (HCV) a worldwide health problem and the most frequent cause of chronic hepatitis, liver cirrhosis and hepatocelular carcinoma, a practical score system to perform the histopathologic diagnosis does not exist. Objective: To increase the competence of pathologists in the diagnosis of HCV at "Abel Santamaria Cuadrado" University Hospital from January 2002 to July 2008. Design: A technological innovation was created writing a book with electronically- processed diagrams and the study of HCV-biopsies by means of a descriptive and cross-sectional design. Subjects and Method: Universe: 236 biopsies with the diagnosis of HCV. Sample: 117 biopsies having the diagnosis of Chronic- HCV (the total during the period). Age, sex, type of histological lesion; diagnostic correspondence, the degree of the lesion and stage of the fibrosis in respect of the age were considered. Descriptive Statistics was used to sum up the categorical and continuing quantitative variables and the verification of frequencies through calculation and/or association of variables X², OR. Results: A system of representative histological draws for the classification of chronic viral hepatitis (Ishak, 1995) was created. Chronic-HCV was more frequent between ages 35-54, female sex, and moderate necro-inflammatory activityreached up to 60.6% between 35 and 44 years old. Conclusion: It was confirmed that the system of draws makes possible a better standardization of the diagnosis in teams and provides a more suitable learning of the disease.

Keywords : human viral hepatitis; fibrosis; learning.

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