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Revista de Ciencias Médicas de Pinar del Río

On-line version ISSN 1561-3194

Abstract

CIRION MARTINEZ, Gladys Rafaela; HERRERA PEREZ, Miguel Ángel  and  SANABRIA NEGRIN, José Guillermo. Cyto-histological correlation of the pre-malignant and malignant lesions of the cervix. Rev Ciencias Médicas [online]. 2010, vol.14, n.1, pp.92-103. ISSN 1561-3194.

Quality control is compulsory for any programs, being of a great importance the diagnosis of the lesions in the cervix, cervical cancer is the second cause of death in women. Objectives: To determine the cyto-histological correlation of the pre-malignant and malignant lesions of the cervix. This research paper was carried out at "Abel Santamaria Cuadrado" University Hospital during 2004-2007. Design: An external validation study was conducted on the organic cytology of the cervix by means of an observation, descriptive and cross-sectional design. Subjects and method: Universe: 7174 women with cervix biopsy specimen, out of them 3240 came from the "Programa de Deteccion Precoz del Cancer Cervico-Uterino (PDPCCU)" (Program for the Early Detection of Cervical Cancer).  Age, diagnostic correspondence with the cytology and the biopsy; as well as the yield of the organic cytology  according to the type of lesion; using Descriptive Statistics to sum up the categorical and continuing quantitative variables. Sensitivity and specificity of the diagnosis was calculated. Results:  A progressive increase in the cervix biopsies performed and a significant increment of the cases recorded in the Program for the Early Detection of Cervical Cancer were observed; diagnosis of the premalignant lesions prevailed and the most frequent were those identified of Cervical Intraepithelial Neoplasia (CIN-1). Cyto-histological correlation and sensitivity increased with the severity of the lesions. Conclusion: It was proved that the quality control maintains the international standards.

Keywords : cervix uteri; neoplasias del cuello uterino; diagnosis; quality control.

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