Resumo

ORIOLO ESTRADA, Rosaevelyn; SANABRIA NEGRIN, José Guillermo  e  ORIOLO PEREZ, Leonardo. Effectiveness of midazolam against anxiety in children aged 1 to 3 years old who underwent surgery. Rev Ciencias Médicas [online]. 2014, vol.18, n.3, pp. 388-400. ISSN 1561-3194.

Introduction: any surgical procedure creates anxiety, especially in children, and also parental separation anxiety is added at the entrance to the operating room. Objective: to determine the effectiveness of midazolam syrup against anxiety in children aged 1 to 3 years old who were undergoing surgery and requiring general anesthesia, in Pepe Portilla Provincial Pediatric Teaching Hospital of Pinar del Rio, in the period 2008-2009. Material and method: a prospective, longitudinal and cohort study of cases and control was carried out in children (ASA I or II). Thirty received the syrup by drops, in a dose of 0.5 mg/kg, and 60 controls who did not receive it, under informed parental consent. Sedation period, vital signs, adverse reactions and degree of satisfaction of parents and staff of the operating room were measured. Frequencies compared using the chi-square test also calculated. Results: the sample was homogeneous by sex, age and type of surgery performed (p> 0.05). Sedation was obtained from 10 minutes on in 24 out of 30 children. Bradypnea was the only adverse effect observed with midazolam syrup in 7 children. The controls (100% tachypneic and crying children). 76.7% of the parents and 100% of the medical staff were satisfied with the sedative effect of midazolam. Conclusions: this is the first time this drug has been used as a premedication in children aged 1 to 3 years old, and the effectiveness and efficacy has been proved, with few adverse and wide acceptability and satisfaction by the parents and the medical staff.

Palavras-chave : Midazolam; Conscious sedation; Preschool child.

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