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Revista de Ciencias Médicas de Pinar del Río
On-line version ISSN 1561-3194
Abstract
PAVON ROJAS, Alejandro Jarol; GONZALEZ, Sergio Orlando Escalona and CISNERO REYES, Lisvan. Physical mechanisms involved in cardiovascular damage of COVID-19 carriers. Rev Ciencias Médicas [online]. 2020, vol.24, n.5, e4482. Epub Nov 24, 2020. ISSN 1561-3194.
Introduction:
COVID-19 is a new disease which provokes damage to human health, with direct impact on the cardiovascular system.
Objective:
to describe the pathophysiogenic mechanisms involved in the cardiovascular damage in COVID-19 patients.
Method:
a literature review was carried out, through articles retrieved in PubMed, SciELO, EBSCO and ClinicalKey, using 27 references.
Development:
different pathophysiogenic mechanisms are associated with cardiovascular damage in COVID-19 patients; among them direct myocardial injury, viral invasion of cardiomyocytes, alteration of myocardial supply-demand index, atheroma-plaque rupture and coronary thrombosis, systemic inflammation and electrolyte imbalances.
Conclusions:
determining the mechanisms involved in cardiovascular damage is a fundamental pillar as a preventive and screening strategy in COVID-19 patients. Inflammatory response, secondary hemodynamic changes to the viral process, as well as hypoxemia, are mechanisms of negative impact on cardiovascular health, leading to the development of acute cardiac injury.
Keywords : CARDIOVASCULAR DISEASES; CORONAVIRUS INFECTIONS/PHYSIOPATHOLOGY.