Introduction:

breast cancer is a health problem, its metabolic alterations and tumor markers can become a prognostic tool.

Objective:

to determine the influence of the modifications and association of tumor marker 15.3, the degree of positivity of estrogen receptors, progestin receptors, HER-2 receptors and histological diagnosis on the clinical characteristics, response to treatment and evolution of patients with breast cancer.

Methods:

an analytical, retrospective and cross-sectional observational study was carried out in 45 patients with breast cancer treated at the Third Congress Oncology Center in Pinar del Río, Cuba, in the year 2022.

Results:

we found a predominance of patients between 50-59 years old, with overweight and different degrees of obesity, with 60 % of both groups, according to BMI, white skin color, absence of family pathological antecedents, with university education level, with ductal histological diagnosis, tumors between 0.1 - 2.0 cm tumor, time of evolution between one and five years and left breast involvement.

Conclusions:

in this study we determined the influence that the modifications and association of the tumor marker 15.3, the degree of positivity of estrogen receptors, progestin receptors, HER-2 receptors and histological diagnosis have on the clinical characteristics, the response to treatment and the evolution of patients with breast cancer.

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