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Gaceta Médica Espirituana

On-line version ISSN 1608-8921

Abstract

PERDOMO PULIDO, Yusely et al. Skin sensitization in allergic patients, using Valergen mite extracts. Gac Méd Espirit [online]. 2020, vol.22, n.1, pp.81-89.  Epub Apr 01, 2020. ISSN 1608-8921.

Background:

Allergic diseases are a global health problem and mites are among its main etiological agents.

Objective:

To describe the behavior of skin sensitization in allergic patients, using Valergen mite extracts.

Methodology:

A cross-sectional observational investigation was carried out with 488 allergic patients being 5 and 55 years old, from both sexes; which were made skin tests with allergenic extracts of mites in the period 2010-2017.

Results:

90.8 % of the patients showed positive skin sensitization to the extracts used, 58.4 % were from between the 5 and 14 age group, 51.2 % were female, patients with rhinitis and asthma predominated; skin sensitization in patients with these pathologies reached a positivity of 90.1 % and 90.6 % respectively; 38.5 % of patients had a mite with greater positivity to VALERGEN-DP (Dermatophagoides pteronyssinus).

Conclusions:

Nationally produced extracts of VALERGEN-DP mites (Dermatophagoides pteronyssinus) showed high skin sensitization in the allergic patients under study; the most positive mite was VALERGEN-DP (Dermatophagoides pteronyssinus), followed by VALERGEN-BT (Blomia tropicalis).

Keywords : Allergen; hypersensitivity; mites; mites extracts; allergic patients; cutaneous reactivity; skin manifestations.

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