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Gaceta Médica Espirituana

versión On-line ISSN 1608-8921


PULIDO ESPINOSA, Cosme Daniel et al. Diffuse large B-cell non-Hodgkin's lymphoma as primary ovarian lymphoma. Case presentation. Gac Méd Espirit [online]. 2023, vol.25, n.2, 2469.  Epub 05-Mayo-2023. ISSN 1608-8921.


Primary ovarian lymphomas are uncommon, 1% of these malignancies occur in the ovary, and 1.5% of all ovarian malignancies are lymphomas. The most common histologic types are diffuse large B-cell non-Hodgkin's lymphoma and BurKitt's lymphoma; treatment consists of surgery combined with chemotherapy.


To report a case of primary ovarian diffuse large B-cell non-Hodgkin lymphoma.

Case presentation:

A 39-year-old female case is presented, with a personal pathological history; she went to the gynecology emergency service because she presented diffuse abdominal pain that was not relieved by analgesics. Physical examination revealed superficial and deep pain on palpation in the hypochondrium and right illiac fossa with a palpable tumor mass. Right adnexal ultrasound showed an image of low echogenicity and at the emergency laparoscopy, it was diagnosed as a tumor-like formation that appeared to correspond to the right ovary. She underwent a hysterectomy with double adnexectomy. The anatomopathologic diagnosis was primary ovarian non-Hodgkin's lymphoma.


The patient in the presented case had an oligosymptomatic clinical presentation. Confirmation of the disease was obtained from a surgical sample, which means that B-cell non-Hodgkin's lymphoma is difficult to diagnose and although it is uncommon, it should always be considered in the differential diagnosis of unilateral ovarian tumors.

Palabras clave : Lymphoma non-Hodgkin; lymphoma large b-cell diffuse; ovarian neoplasms; case reports; ovarian tumor; tumor.

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