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Gaceta Médica Espirituana

versión On-line ISSN 1608-8921

Resumen

CASTILLO LOPEZ, Wardy; MONTERO LOPEZ, Izaida Lis; DIAZ MONTERO, Adrián Ernesto  y  VALDES CABODEVILLA, Regla Cristina. Use of labetalol vs nifedipine in preeclampsia. Gac Méd Espirit [online]. 2023, vol.25, n.2, 2545.  Epub 30-Mayo-2023. ISSN 1608-8921.

Background:

Pre-eclampsia is a generalized vasoconstriction state associated with vascular epithelial dysfunction rather than the vasodilation characteristic of pregnancy, characterized by proteinuric hypertension from the 20th week of pregnancy, sometimes associated with edema; it also causes health risks to the mother and fetus. Traditional clinical treatment uses oral antihypertensive drugs, among these labetalol and extended-release nifedipine are included.

Objective:

To analyze the efficacy of labetalol and nifedipine as an antihypertensive treatment in pre-eclampsia.

Methodology:

Reference sources found in Google Scholar, Science Direct, SciELO, Pubmed, Medes and Elsevier were used. Out of 211 sources, 31 were selected according to inclusion and exclusion criteria.

Conclusions:

It has been determined by majority consensus that oral nifedipine is more effective than labetalol in pre-eclampsia treatment.

Palabras clave : Preeclampsia; hypertension pregnancy-induced; labetalol therapeutic use; nifedipine therapeutic use.

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