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Revista Cubana de Angiología y Cirugía Vascular

versión On-line ISSN 1682-0037


CASTANEIRA JORGE, Elaine  y  FEBLES SANABRIA, Ridel Jesús. Foot ulcer recurrence in diabetic patients who received heberprot-p® treatment. Rev Cubana Angiol Cir Vasc [online]. 2020, vol.21, n.2, e135.  Epub 01-Ago-2020. ISSN 1682-0037.


Heberprot-P® is a novel medicine, unique among its kind, prescribed for diabetic foot ulcer therapy.


To evaluate frequency and characteristics of foot ulcer recurrence among diabetic patients treated with Heberprot-P®.


A descriptive-retrospective research was carried out. The study population consisted of 16 patients with diabetic foot ulcer recurrence from among the 841 treated with Heberprot-P® in polyclinics and hospitals in Matanzas Province from January to December 2018. The variables reviewed were taken to a database, and the results obtained were represented in charts and expressed in absolute and relative frequencies. The ethical considerations required for this study were respected.


The age group 61-75 years and type 2 diabetic patients were the most affected. There were no differences between both sexes. Neuropathic diabetic foot with Wagner 2 severity appeared more frequently. Likewise, after the first injury and recurrence, a large number of patients with the disease were observed at 13-16 weeks, 56.2% of whom, were administered, during the first injury, 6-12 doses of Heberprot-P®. The total closure of the lesion was the most found outcome in the study population, and 1.9% of the treated patients presented recurrence of this.


The frequency and characteristics of foot ulcer recurrence in diabetic patients treated with Heberprot-P® were exposed.

Palabras clave : diabetes mellitus; diabetic foot ulcer; recurrence.

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