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Revista Médica Electrónica

On-line version ISSN 1684-1824

Abstract

GONZALEZ GIL, Alcides et al. Antioxidant enzymes in saccharose-induced hyperglycemia and hyperlipidemia in Wistar rats. Rev. Med. Electrón. [online]. 2013, vol.35, n.2, pp.95-104. ISSN 1684-1824.

The work we accomplished evaluated the activity of the catalase antioxidant and dismutase superoxide enzymes in the experimental model of saccharose induced hyperlipidemia in Wistar rats, for what we determined the glicemia and plasmatic fluids and the levels of dismutase superoxide and catalase specific enzymatic activity. There they were significant increases in glicemia and triacylglycerides related with a saccharose-rich diet. At the fourth month of the study we observed an increase of the enzymes in the group with a saccharose-rich diet, with significant increases only for the catalase. It was observed a strong correlation  between the triacylglyceride levels of the studied group in the last month of experimentation and the values obtained in the catalase enzymatic activity.

Keywords : oxidative stress; free radicals; antioxidant enzymes; catalase, dismutase superoxide.

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