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Revista Médica Electrónica

versión On-line ISSN 1684-1824

Resumen

ARREDONDO BRUCE, Alfredo; HUERTA RAMIREZ, Janet; DOMINGUEZ CALDERON, Tomás  y  PEREZ ZAYAS, Jesús. Presentation of a patient carrying a progressive supra-nuclear paralysis. Rev.Med.Electrón. [online]. 2016, vol.38, n.6, pp.887-893. ISSN 1684-1824.

The progressive supra-nuclear paralysis (PSP) or Steele-Richardson-Olszewsky’s syndrome is a strange, degenerative illness produced by the deterioration and gradual death of brain selected areas. We present the case of a female patient, aged 80 years, who refers postural instability, frequent falls and cognitive dysfunctions. She also presents stiffness in retrocollis in the back of the neck, fall of eyelids, left hand shaking, dysarthric and incoherent language, and shaking of both hands in coins counting. The cardiovascular examination showed 2nd increased beat, systolic murmur III/IV in mitral focus, AT 160/90 mm of Hg, edemas in both inferior members, hearth frequency of 110 beats/min., and jugular ingurgitation.  The rest of the physical examination was normal. The etiologic diagnosis was progressive supranuclear paralysis and dilated cardiomyopathy. The tau protein is important in the maintenance of the neuronal morphology through microtubules formation, the different proportions and locations, causing the Richardson’s syndrome. The most common symptoms of this entity are postural instability and frequent falls, dysarthria, hypokinesia and visual alterations. Magnetic resonance and functional neuroimaging help the diagnosis.

Palabras clave : neurodegeneration; supranuclear paralysis; Parkinsonism.

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